APTEEUS offers access to automated cell screening technology in partnership with patient organizations, research teams and pharmaceutical companies
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Technologies & Facilities
High throughput sequencing platforms, consisting of
* Analysis platform (SeqOIA-Gen) for qualification, extraction, preparation and sequencing
* Bioinformatics platform (SeqOIA-IT) for data processing, storage, archiving
* Interpretation platform (SeqOIA-LMG): brings together the expert biologists from the Genomic Medicine Laboratories (LMG) who will validate the reports of the medical analyzes of the SeqOIA Medical Biology laboratory (LBM SeqOIA).
Auragen offers access to very high throughput sequencing to players involved in oncology and in the management of rare diseases. DNA / RNA extraction and sequencing are carried out in the medical biology laboratory located in the premises of the HCL (Hospices Civils de Lyon). The bioinformatics processing of the sequences is carried out on the sites of the CHUGA (CHU Grenoble-Alpes) and the CLB ( Center Léon Bérard ). The data are analyzed and interpreted in the various partner establishments of the GCS by AURAGEN experts and colleagues competent in the patient’s pathology.
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I-Stem has a platform for high-throughput screening of libraries of chemical molecules on embryonic stem cells or iPS with genetic defects.
The laboratory has a high-performance robotic platform with miniaturization and standardization of cellular tests as well as the performance of large-scale screening campaigns (10 000 to 40 000 tests per screening campaign) under sterile and reproducible conditions.
High Throughput Screening, chemical and target libraries
Provided by PCBIS - PLATFORM OF INTEGRATIVE CHEMICAL BIOLOGY OF STRASBOURG
The Platform of Integrative Chemical Biology of Strasbourg (PCBIS) gives access to High Throughput Screening (HTS), chemical libraries and target libraries to academic and private laboratories. The platform evaluates the ADME properties of active molecules: Ciblothèque
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CCG offers various gene expression profiling platforms that may be used for high-throughput production and cross platform validations.
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The CCGA offers a broad range of methods for RNA e.g. RNAseq, Single Cell transcriptomics or isoform sequencing as well as DNA e.g. whole genome sequencing, amplicon sequencing or exome sequencing.
Visit websiteGenome-wide and targeted Next-Generation-Sequencing
Provided by DRESDEN-CONCEPT GENOME CENTER (DCGC)
Next generation sequencing (NGS) and associated technologies are available to researchers in the area of life sciences on the Dresden Campus of DCGC. It provides strong expertise in the areas of:
(1) Single cell applications;
(2) De novo genome sequencing and assemblies; and
(3) A broad range of short read-based sequencing application.
Services provided by EU-OPENSCREEN include
• high-throughput compound/ drug screening (HTS): HTS of an assay against the EU-OPENSCREEN chemical collection (> 100,000 compounds); in silico profiling; hit selection; confirmatory screening; basic
counter screening; basic SAR based on screening data; QC of confirmed hits
• access to a unique European compound collection: EU-OPENSCREEN chemical collection (> 100,000 compounds)
Through Euro-BioImaging, life scientists can access imaging instruments including biological (e.g. microscopy, mass spectrometryand, fluorescence spectroscopy based imaging) and multi-modal molecular and medical (PET, MRI, CT, SPECT) imaging, expertise, and data management services
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