CCG offers various gene expression profiling platforms that may be used for high-throughput production and cross platform validations.
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The CCGA offers a broad range of methods for RNA e.g. RNAseq, Single Cell transcriptomics or isoform sequencing as well as DNA e.g. whole genome sequencing, amplicon sequencing or exome sequencing.
Visit websiteGenome-wide and targeted Next-Generation-Sequencing
Provided by DRESDEN-CONCEPT GENOME CENTER (DCGC)
Next generation sequencing (NGS) and associated technologies are available to researchers in the area of life sciences on the Dresden Campus of DCGC. It provides strong expertise in the areas of:
(1) Single cell applications;
(2) De novo genome sequencing and assemblies; and
(3) A broad range of short read-based sequencing application.
Services provided by EU-OPENSCREEN include
• high-throughput compound/ drug screening (HTS): HTS of an assay against the EU-OPENSCREEN chemical collection (> 100,000 compounds); in silico profiling; hit selection; confirmatory screening; basic
counter screening; basic SAR based on screening data; QC of confirmed hits
• access to a unique European compound collection: EU-OPENSCREEN chemical collection (> 100,000 compounds)
Through Euro-BioImaging, life scientists can access imaging instruments including biological (e.g. microscopy, mass spectrometryand, fluorescence spectroscopy based imaging) and multi-modal molecular and medical (PET, MRI, CT, SPECT) imaging, expertise, and data management services
Visit websiteESGI provides access to new genomic technologies and analytic tools, including
* DNA analysis
* Long Read analysis
* Transcriptome Analysis
*3D genomics
*single cell analysis
*Epigenomic Analysis
Genomics and Proteomics core facility
Provided by GERMAN CANCER RESEARCH CENTER GENOMICS & PROTEOMICS CORE FACILITY
Genomics and Proteomics Core Facility has integrated Many different services:
The Microarray Unit performs expression profiling of mRNA and miRNA, Genotyping and genome-wide methylation analysis.
High-Throughput sequencing is offered and monoclonal antibodies, stable isogenic recombinant cell lines and a clone and vector repository are available.
Additionally we provide booking of central GPCF equipment like Real Time PCR machines, sample preparation robots or SilverQuant scanning systems or the wetlab wiki, which allows you to share and discuss protocols with your colleagues at DKFZ.
The center offers high-throughput sequencing services on the latest Illumina Next Generation Sequencer NovaSeq6000, Oxford Nanopore Technologies Sequencer PromethION and Pacific Bioscience Sequel.
Visit websiteCentralized Next Generation Sequencing (NGS) services are complemented with existing decentralized NGS and bioinformatics expertise of the WGGC partners. Such expertise covers most aspects of NGS research, encompassing capabilities in human and medical genetics as well as onco and plant genomics.
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