Published by JPP
Research and Drug DevelopmentDrug DiscoveryDrug RepurposingGenericOverview of the drug repositioning benefits both its public health benefits and its commercial value.
View this resource Bookmark this resourcePublished by Medicines Discovery Catapult
Drug DiscoveryTarget IdentificationSmall MoleculesThis guideline is a summary presentation from the Medicines Discovery Catapult (MDC) webinars. The aim was to create a resource of modern drug discovery knowledge to support small companies who are developing their own medicines. The guideline is focused on preclinical research with an emphasis on small molecules in the following topics:
• What makes, and how to identify, a good target
• Methods to identify the chemical compound which would become the drug
• How to optimise that drug
• How to test it works in models of disease
• And how to demonstrate that it would be safe to dose in humans
Published by Discovery Medicine
Animal ModelDrug DiscoveryHigh Throughput ScreeningCell ModelTarget IdentificationBiologicsSmall MoleculesDiscovery Medicine is an evidence-based, peer-reviewed, open-access, and scholarly biomedical journal indexed in MEDLINE/PubMed by the U.S. National Library of Medicine. It is a premier source of important information, knowledge, and insights in translational and clinical research
View this resource Bookmark this resourcePublished by Alzheimers Dement (N Y).
Drug DiscoveryTarget ValidationThis article provides a brief overview of the processes of drug discovery and development. The aim is to help scientists whose research may be relevant to drug discovery and/or development to frame their research report in a way that appropriately places their findings within the drug discovery and development process and thereby support effective translation of preclinical research to humans.
View this resource Bookmark this resourcePublished by Technology Networks Drug Discoery
Drug DiscoveryTarget-Based ScreeningPhenotypic ScreeningTarget-Based Screening has been the method of choice in drug discovery for the past two decades, but Phenotypic Screening is having something of a renaissance. In this article the authors look at the advantages and applications of both.
View this resource Bookmark this resourcePublished by European Journal of Medicinal Chemistry
Research and Drug DevelopmentClinical TrialDrug DiscoveryDrug RepurposingLead MoleculeThis review provides different approaches for Drug Repurposing and addresses recent developments and future scope of drug repositioning strategies. In addition provides a list of repurposed drugs and repurposing resources.
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Research and Drug DevelopmentIntellectual PropertyDrug DiscoveryDrug RepurposingBig DataRare DiseaseNeglected DiseaseCrowdfundingPrecision MedicineArticle that cover the most significant challenges and opportunities in Drug Repurposing.
View this resource Bookmark this resourcePublished by IRDiRC
Research and Drug DevelopmentDrug DiscoveryBioassayBio-Analytical AssayMeasurement of drug concentrations in biological matrices (such as serum, plasma, blood, urine, and saliva) is an important aspect of drug development. These methods provide data to support the Safety and effectiveness of drugs, which may be needed to support applications for new drugs in regulatory pathways
View this resource Bookmark this resourceWeb resource for basic and clinical research in Gene Therapy, cell therapy, and genetic vaccines. In addition, it provides an overview of the different international regulations and guidelines associated with clinical Gene Therapy trials.
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