Provided by CHEMBIONET: RESOURCE NETWORK SUPPORTING ACADEMIC CHEMICAL BIOLOGY RESEARCH
Chembionet provides chemists with bioprofiles for their unique synthetic molecules and biologists developing unique assay systems, with access to high throughput technologies to identify compounds useful for dosage dependent, temporally or locally controlled interference with biological functions.
Visit websiteProvided by CARE AND TRIAL SITE REGISTRY FOR NEUROMUSCULAR AND NEURODEGENERATIVE DISEASES (CTSR)
Care and Trial Site Registry (CTSR) helps clinical investigators select trial sites as well as to help to identify potential partners for upcoming research projects.
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CCG offers various gene expression profiling platforms that may be used for high-throughput production and cross platform validations.
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The CCGA offers a broad range of methods for RNA e.g. RNAseq, Single Cell transcriptomics or isoform sequencing as well as DNA e.g. whole genome sequencing, amplicon sequencing or exome sequencing.
Visit websiteProvided by DRESDEN-CONCEPT GENOME CENTER (DCGC)
Next generation sequencing (NGS) and associated technologies are available to researchers in the area of life sciences on the Dresden Campus of DCGC. It provides strong expertise in the areas of:
(1) Single cell applications;
(2) De novo genome sequencing and assemblies; and
(3) A broad range of short read-based sequencing application.
Services provided by EU-OPENSCREEN include
• high-throughput compound/ drug screening (HTS): HTS of an assay against the EU-OPENSCREEN chemical collection (> 100,000 compounds); in silico profiling; hit selection; confirmatory screening; basic
counter screening; basic SAR based on screening data; QC of confirmed hits
• access to a unique European compound collection: EU-OPENSCREEN chemical collection (> 100,000 compounds)
Services provided by EU-OPENSCREEN include
• assay adaption: This assay adaptation process will involve a strong emphasis on quality, including: quality control of reagents; (patho-)physiological relevance; pharmacological consistency; robustness; minimised variability; and tracking of statistical descriptors (e.g. signal to background and the Z’ factor)
• chemical optimization and profiling of preliminary ‘hits’
• bioprofiling of donated compounds: All compounds donated by the user which enter the EU-OPENSCREEN ERIC compound collection are characterised and annotated for basic physico-chemical (e.g. identity, solubility, light absorbance and fluorescence) and essential to know biological properties (cytotoxicity, antibiotic, antifungal etc.) by testing in a standard panel of assays.
• provision of standardised data: All data generated through QC/bioprofiling and screening activities will be published in EU-OPENSCREEN’s open-access database with an optional ‘grace’ period (i.e. delayed publication of data). Large-scale open-access data provide the basis for computational data integration to obtain a systematic view, allow for prediction of drug-target interactions and networks as well as of adverse effects and drug combinations. The access to the EU-OPENSCREEN database will utilize the facilities of ChEMBL.
EU-OPENSCREEN provides training and education activities in the aread of assay development, assay technologies, instrumentation and automation, compound management, and informatics.
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Euro-BioImaging offers numerous courses that teach you how to use various imaging technologies or analyze and process your results. The current portfolio includes:
Biological Imaging Courses
Biomedical Imaging Courses
Training Resources from Industry Partners
MSc degree programmes/MSc level internships/mobility
Through Euro-BioImaging, life scientists can access imaging instruments including biological (e.g. microscopy, mass spectrometryand, fluorescence spectroscopy based imaging) and multi-modal molecular and medical (PET, MRI, CT, SPECT) imaging, expertise, and data management services
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