Global registry for human pluripotent stem cell lines

Provided by Human Pluripotent Stem Cell Registry (hPSCreg)

HPSCREG

It aims to provide to the community

a central and searchable hub for available hPSC-lines
a central registry of clinical studies based on hPSC-lines
a standardized identifier for hPSC-lines and register of these standard names
a trustworthy data source for hPSC-lines by verifying the ethical and biological conformity of registered lines based on community standards
comparability of quality standards in hPSC research
certification of quality and ethical provenance of hPSC-lines
a platform where any scientist or institution generating or working with PSC lines can register their cell lines, projects or clinical studies

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MD-NET – Network for Muscular Dystrophy

Provided by MD-NET

MD NET

Guidelines and advice for professionals and patients
Best Practice Guidelines on molecular diagnostics in Duchenne / Becker muscular dystrophies (2010)
Diagnosis and management of Duchenne muscular dystrophy
Consensus statement for standard of care in spinal muscular atrophy (2007)
Heart failure DEGAM guideline No. 9 (2006)
Diagnostics and therapeutic approaches for mitochondrial disease in children and adolescents – S2 guideline (2009)
Diagnosis of myopathies (2008)
Guidelines for the molecular genetic diagnosis of muscular dystrophies Duchenne and Becker (1999)
Consensus statement on standard of care for congenital muscular dystrophies (2010)

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Genomics and Proteomics core facility

Provided by GERMAN CANCER RESEARCH CENTER GENOMICS & PROTEOMICS CORE FACILITY

Genomics and Proteomics Core Facility has integrated Many different services:
The Microarray Unit performs expression profiling of mRNA and miRNA, Genotyping and genome-wide methylation analysis.
High-Throughput sequencing is offered and monoclonal antibodies, stable isogenic recombinant cell lines and a clone and vector repository are available.
Additionally we provide booking of central GPCF equipment like Real Time PCR machines, sample preparation robots or SilverQuant scanning systems or the wetlab wiki, which allows you to share and discuss protocols with your colleagues at DKFZ.

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 Mouse Models

Provided by INFRAFRONTIER

infrafrontier

Services offered by INFRAFRONTIER include
• archiving and distribution of scientifically valuable mutant mouse strains
• rodent model development (mouse and rat) using gene targeting in embryonic ES-cells or CRISPR/CAS9 technologies
• systemic phenotyping of mutant mice for a whole-organism view on gene function
• germ-free (axenic) mice
• validated genetically engineered mouse models of cancer

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Training on mouse models

Provided by INFRAFRONTIER

infrafrontier

The INFRAFRONTIER Research Infrastructure and its partners offer a wide range of state-of-the-art training opportunities: Mouse clinics in different European countries provide outstanding trainings in first-line mouse phenotyping as well as specialised phenotyping courses covering e.g. mouse osteology and mouse blood and lymphatic vessel phenotyping.

The INFRAFRONTIER courses cover unique training opportunities in mouse model development as well as hands on cryopreservation courses offered by EMMA partners for many years.

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Sequencing services

Provided by NCCT - NGS COMPETENCE CENTER TÜBINGEN

WGGC

The center offers high-throughput sequencing services on the latest Illumina Next Generation Sequencer NovaSeq6000, Oxford Nanopore Technologies Sequencer PromethION and Pacific Bioscience Sequel.

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Next Generation Sequencing services

Provided by West German Genome Center (WGGC)

WGGC

Centralized Next Generation Sequencing (NGS) services are complemented with existing decentralized NGS and bioinformatics expertise of the WGGC partners. Such expertise covers most aspects of NGS research, encompassing capabilities in human and medical genetics as well as onco and plant genomics.

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central compound collection for screening

Provided by CHEMBIONET: RESOURCE NETWORK SUPPORTING ACADEMIC CHEMICAL BIOLOGY RESEARCH

ChemBioNet

Chembionet provides chemists with bioprofiles for their unique synthetic molecules and biologists developing unique assay systems, with access to high throughput technologies to identify compounds useful for dosage dependent, temporally or locally controlled interference with biological functions.

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