GenOmics 2024

Published by FONDATION MALADIES RARES

Genomics

The Fondation Maladies Rares is pleased to announce the launch of its “GenOmics” 2024 call for projects.

The aim of this AAP is to support hypothesis-driven research projects aimed at exploring the genetic and molecular basis of rare diseases using NGS approaches (WES, WGS, RNA-seq, small RNA-seq, ChIP-seq, Methyl-seq, etc.).

Support from the Fondation Maladies Rares will give project leaders access to innovative high-throughput sequencing technologies for the analysis of exomes, genomes, transcriptomes or epigenomes.

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Towards a Concrete Improvement in the Quality of Life of Patients with Autoimmune Myasthenia

Published by FONDATION MALADIES RARES

Autoimmune Myasthenia

The Fondation Maladies Rares and UCB have joined forces to offer a €30, 000 research grant to a humanities and social sciences (HSS) research project focused on findingconcrete, short-term ways ofimproving the life course of patients suffering from generalized autoimmune myasthenia gravis.

The grant will be awarded to a research project focusing on the individual, family and/or social consequences specifically linked to generalized autoimmune myasthenia gravis, in order to gain a better understanding of the impact of this disease, and in particular muscular fatigability, on quality of life at the level of the individual, couple or family, for example.

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Bio-printing of Living Cells for Regenerative Medicine

Published by European Commission (EC)

Regenerative Medicine

Regenerative medicine is a branch of translational research in tissue engineering and molecular biology which deals with the “process of replacing, engineering or regenerating human cells, tissues or organs to restore or establish normal function”. 3D-printing in general is considered an advanced manufacturing technique and 3D-printing of non-viable biomaterials to serve e.g. as scaffold for cell growth or as structure for medical devices is already broadly used.

However, bio-printing technology involving living cells is still in early stages of development, but has a huge potential for tissue engineering, drug testing and other biomedical applications. Tissue-specific functional 3D bio-printing is a new approach for transplantation applications in regenerative medicine, relying on the fabrication of tissues and organs with respect to the desired shape and function and their delivery and application in vivo. “In-situ bio-printing” known as printing cells and biomaterials directly onto or in a patient, or 4D bio-printing, which introduces a “time” variable that allows 3D printed materials to change shape or function when external stimulus is applied, are recent developments facing multiple additional challenges.

Despite some success of 3D bio-printing with thin tissue, thick tissue and complex organs remain a bottleneck because it is difficult to sufficiently mimic their metabolic needs, and the scientific knowledge about their intimate architecture and interplay with other tissues are not sufficiently elucidated. Next to these limitations are a lack of standardised manufacturing protocols and standardised bio-ink formulations with tuneable properties, unstable cellular behaviour, material biocompatibility and printability, etc. Taken together, 3D bio-printing is confronted with several challenges that currently hamper its large-scale deployment.

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Developing EU Methodological Frameworks for Clinical/Performance Evaluation and Post-market Clinical/Performance Follow-up of Medical Devices and In Vitro Diagnostic Medical Devices (IVDs)

Published by European Commission (EC)

Medical DeviceClinic

This topic aims at supporting activities that are enabling or contributing to one or several expected impacts of destination 6 “Maintaining an innovative, sustainable and globally competitive health industry”.

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Innovative and Customizable Services for EOSC Exchange

Published by European Commission (EC)

European Open Science Cloud

The aim is to provide researchers with a set of highly innovative new services via the EOSC Exchange. These would exploit, in a structural way, the cloud-based EOSC Core technologies and horizontal European compute and data management capacities that are part of the Minimum Viable EOSC platform in production.

To be customizable and scalable, all developments should be tested against 2-3 real life use cases from a variety of scientific domains. The proposals should cooperate with the EOSC Testbed facility (to be funded under HORIZON-INFRA-2023-EOSC-01-04) as well as other relevant and related projects and e-Infrastructures and large user communities. Joint use cases and testing across individual project boundaries are encouraged.

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Enabling a Network of EOSC Federated and Trustworthy Repositories and Enhancing the Framework of Generic and Discipline Specific Services for Data and other Research Digital Objects

Published by European Commission (EC)

European Open Science Cloud

The aim is to provide researchers with a set of highly innovative new services via the EOSC Exchange. These would exploit, in a structural way, the cloud-based EOSC Core technologies and horizontal European compute and data management capacities that are part of the Minimum Viable EOSC platform in production.

To be customizable and scalable, all developments should be tested against 2-3 real life use cases from a variety of scientific domains. The proposals should cooperate with the EOSC Testbed facility (to be funded under HORIZON-INFRA-2023-EOSC-01-04) as well as other relevant and related projects and e-Infrastructures and large user communities. Joint use cases and testing across individual project boundaries are encouraged.

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MSCA COFUND 2024

Published by European Commission (EC)

MSCACOFUND

Applicants submit proposals for new or existing doctoral or postdoctoral programmes with an impact on the enhancement of human resources in R&I at regional, national or international level. These programmes will be co-funded by MSCA COFUND.

Proposed programmes can cover any research disciplines (“bottom-up”), but exceptionally can also focus on specific disciplines, notably when they are based on national or regional Research and Innovation Strategies for Smart Specialisation (RIS3 strategies). In this case, the range of covered disciplines should allow reasonable flexibility for the researchers to define their topic.

Funding synergies with Cohesion policy funds and the Recovery and Resilience Facility (RRF) are strongly encouraged[1],[2].

A Career Development Plan must be jointly established by the supervisor and each recruited researcher upon recruitment. In addition to research objectives, this Plan comprises the researcher’s training and career needs, including training on transferable skills, teaching, planning for publications and participation in conferences and events aimed at opening science and research to citizens. The Plan must be established at the beginning of the recruitment and should be revised (and updated where needed) within 18 months.

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MSCA International Cooperation 2024

Published by European Commission (EC)

MSCA

The objective is to foster international cooperation in MSCA in Horizon Europe, through a dedicated support action to complement and ensure coordination between existing promotion channels at local level, and ensure consistency with formal R&I policy dialogues at bilateral and regional levels

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ERA Talents

Published by European Commission (EC)

ERATalent

Cross-sectoral talent circulation and academia-business collaboration for knowledge transfer is requiring systematising and structuring efforts. Through ERA4You, as one of the ERA Policy Agenda outcomes[1], the European Commission aims to support and incentivise such transformations, towards a more balanced circulation of talents, both trans-nationally and across sectors. Within this scope, ERA Talents aims to support training and mobility of researchers, innovators, and other research and innovation talents across sectors with a particular focus on Widening countries.

Complementary to ERA Chairs, Excellence Hubs, ERA Fellowships and MSCA Staff Exchanges, the ERA Talents scheme promotes innovative inter-sectoral collaboration in research and innovation through cross-sectoral exchange of staff, with a focus on Widening countries. Grants awarded under this topic are expected to collaborate with each other and participate in mutual learning exercises.

Intersectoral mobility. Actions are invited to develop activities in view of realising one or more of the following European Commission’s objectives regarding intersectoral mobility. The European Commission aims at selecting a portfolio of complementary actions where possible.

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