In this section you may find information about technologies and approach in novel drug discovery
Published by JPP
Research and Drug DevelopmentDrug DiscoveryDrug RepurposingGenericOverview of the drug repositioning benefits both its public health benefits and its commercial value.
View this resource Bookmark this resourcePublished by EATRIS
Small MoleculeDrug Discovery GuidelineResearch and Drug DevelopmentDrug RepurposingTarget Validation Drug DevelopmentNCATSNIHThis manual is a comprehensive resource for early drug discovery, providing guidelines for developing therapeutic hypotheses, validating targets and pathways, and establishing proof of concept criteria. It includes analyses of costs at various stages of drug development. The content encompasses critical decision-making points in New Chemical Entity (NCE) development, exploratory Investigational New Drug (IND) processes, and orphan drug designation. Furthermore, it delves into Drug Repurposing and drug delivery technologies, making it an invaluable guide for professionals initiating new drug discovery and development programs.
View this resource Bookmark this resourcePublished by European Journal of Medicinal Chemistry
Research and Drug DevelopmentClinical TrialDrug DiscoveryDrug RepurposingLead MoleculeThis review provides different approaches for Drug Repurposing and addresses recent developments and future scope of drug repositioning strategies. In addition provides a list of repurposed drugs and repurposing resources.
View this resource Bookmark this resourcePublished by Expert Opinion on Drug Discovery
Neglected DiseaseResearch and Drug DevelopmentIntellectual PropertyDrug DiscoveryDrug RepurposingBig DataRare DiseaseCrowdfundingPrecision MedicineArticle that cover the most significant challenges and opportunities in Drug Repurposing.
View this resource Bookmark this resourcePublished by IRDiRC
Orphan DrugDrug RepurposingNCATSResearch and Drug DiscoveryNTU-NCATSFundingThe NTU program aims to improve the process of developing new treatments for diseases by finding new uses for existing therapies that already have cleared several key steps along the development path. Existing or partially developed therapeutic candidates can be repurposed for use in new disease indications
View this resource Bookmark this resourcePublished by Int J Biol Sci.
Drug RepurposingComputational ScienceIn this paper are reviewed computational approaches and highlighted their characteristics to provide references for researchers to develop more powerful approaches. At the same time, the important findings obtained using these approaches are listed
View this resource Bookmark this resourcePublished by Orphanet J Rare Dis.
Data MiningDrug RepurposingThis article reviews the past successes of data mining for Drug Repurposing, and planning for future biomedical research capacity, the DMR Task Force identified four strategic infrastructure investment areas to focus on in order to accelerate rare disease research productivity and drug development: (1) improving the capture and sharing of self-reported patient data, (2) better integration of existing research data, (3) increasing experimental testing capacity, and (4) sharing of rare disease research and development expertise. Additionally, the DMR Task Force also recommended a number of strategies to increase data mining and repurposing opportunities for rare diseases research as well as the development of individualized and precision medicine strategies.
View this resource Bookmark this resourcePublished by Orphanet J Rare Dis.
Data MiningIRDIRCDrug Repurposing(IRDiRC) set up the multi-stakeholder Data Mining and Repurposing (DMR) Task Force to examine the potential of applying biomedical data mining strategies to identify new opportunities to use existing pharmaceutical compounds in new ways and to accelerate the pace of drug development for rare disease patients.
View this resource Bookmark this resource
