a list of 1415 rare diseases that are related to EMMA strains. Please use the search bar to search for rare diseases, gene name, ORPHAcode or EMMA strain.
View this resource Bookmark this resourcePreclinical Studies
In this section you may find relevant information regarding the safety, efficacy and toxicology of the drugs actually used for Rare Diseases as well as:
Good Laboratory Practices (GLPs),
Animal models: juvenile, humanised animal models, disease specific animal models and documents that may support you to correctly use animal models from ethical points of view.
Proof of principle
In silico modelling
ICH: Safety
Published by EMAInternational Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use (ICH)
Genotoxicity StudyTherapeutic Area-SpecificImmunotoxicology StudySafety Pharmacology StudyCarcinogenicity StudyBiotechnological ProductReproductive ToxicologyRepeat-Dose ToxicityToxicokinetics and PharmacokineticsNonclinical Safety in Paediatric MedicinePhotosafety EvaluationThe European Medicines Agency publishes scientific guidelines on human medicines that are harmonised by the International Council for Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use (ICH)
View this resource Bookmark this resourceThe European Medicines Agency publishes scientific guidelines on human medicines that are harmonised by the International Council for Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use (ICH).
View this resource Bookmark this resource